Description

Cambrex is seeking to hire a growth-related Research Investigator & Manager position with a highly motivated individual for the Process Chemistry department. The individual in this position will lead a team of other process chemists while demonstrating expert knowledge in advanced synthetic chemistry principles and practices. The person in this role will work across departments and the site to test and advance innovative processes, hypotheses, methodologies and technology; encourages curiosity and challenges the status quo at the site level in order to foster innovation. Must display expert knowledge in process chemistry and drug substance manufacturing requirements, and substantial experience with GMP practices, CMC principals and ICH guidelines for pharmaceutical development. Deep knowledge and experience with GMP practices, documentation and execution of batch records in a GMP environment is required. The Individual in this position will design and propose new synthetic routes to drug substances and will lead process chemistry portions of customer projects. They will frequently present work internally and externally to clients or regulatory agencies.

• Leads, mentors, manages, develops and provides support to a team of 4-6 organic synthetic process chemists
• Performs multistep organic syntheses, isolation, and purification of targeted products independently. Contribute to the strategic approach used to optimize reactions, isolations, and purifications.
• Proficiently conducts analyses of starting materials, reaction mixtures, intermediates and products using appropriate instrumentation.
• Works closely with other chemistry and analytical laboratory staff to coordinate project activities and resource usage.
• Routinely generates summaries and reports on completed experimental work for internal and external use. Routine presentation of experimental work for internal meetings and teleconferences with customers.
• Works to ensure that teamwork and cooperation exists within the group at all times.
• Conducts laboratory operations in a safe manner.  Maintains familiarity with the company's chemical hygiene plan.  Exhibits safety awareness and safe work practices.
• Follows responsible actions regarding chemical disposal.  Maintains compliance with all regulations at the federal, state, and local levels.
• Addresses routine administrative requirements in a timely fashion.
• Demonstrates effective communication skills (both written and oral).  Participates in project team meetings with customers.
• Works closely with manufacturing and GMP operations to coordinate project-related equipment and activities. Assist in the transfer of processes to the manufacturing team.
• Independently designs and proposes new synthetic processes to produce the drug substance.
• Acts as process chemistry lead for customer projects. Identify critical questions to be answered and set priorities for the process chemistry team.
• Maintains familiarity with applicable literature including organic chemistry and techniques.
• Participates in setting strategy and timing needed for customer proposal requests.
• Works closely with other chemistry and analytical laboratory staff to coordinate project activities and resource usage.
• Routinely generates summaries and reports on completed experimental work for internal and external use. Oral and written presentation of experimental work for internal meetings and teleconferences with customers
• Performs other related duties as assigned.

• PhD in Organic Chemistry with 12+ years of experience in related industry, or MS in Organic Chemistry with 20+ years of experience in related industry, or BS in Organic Chemistry with 22+ years of experience in related industry.
  
• Prior experience leading a team of chemists is strongly preferred.

PI277963369